ea0035p576 | Endocrine tumours and neoplasia | ECE2014
Chiloiro Sabrina
, Bianchi Antonio
, Giampietro Antonella
, Iacovazzo Donato
, Trapasso Barbara
, Piacentini Serena
, Tartaglione Linda
, Lugli Francesca
, De Marinis Laura
Introduction: In 2004, the WHO defined atypical pituitary adenomas (APAs) those with Ki-67 >3%, excessive p53 expression and increased mitotic activity. The usefulness of this classification is still controversial.Aim: To compare the clinical and prognostic features in a series of typical and atypical pituitary adenomas.Materials and methods: We retrospectively reviewed 343 consecutive PAs. APAs represented 18.7% of the cases. ...